摘要
河南医科大学附二院耳鼻喉科从1986年4月至1988年2月应用诱导区域化疗,配合手术、冷冻和放疗等治疗头颈恶性肿瘤80例。病理类型以鳞癌居多,共计61例(76.2％)。动脉灌注药物以PDVM(即平阳霉素、顺氯氨铂、长春新碱、氨甲喋呤)序贯疗法为首选。区域诱导化疗的总有效率为(CR+PR+mR)83.5％,其中显效(CR+PR)为51.2％。
From Apr. 1, 1986 to Feb. 28, 1988, 80 cases of head and neck cancer cases were treated with neoadjuvant regional chemotherapy, followed by surgical resection, cryo-surgery or radiotherapy, satisfactory results were obtained. Of the 80 cases, 50 were males and 25 were famales. 50 patients were over 50 years of age (67-6%). 61 patients (76.2%) were squamous cell carcinoma, including cancers of nasal cavity, paranasal sinuses, nasopharynx, larynx, tonsil, and ear canal etc. The main chemotherapeutic regimen used were Cispladn, Bleo-mycin, MTX and VCR combination. The response rate (CR + PR) was 51.2%, CR + PR + MRwas 83.5% .The role of meoadjuvant chemotherapy in the treatment of head and neck cancers wasdiscussed
出处
《癌症》
SCIE
CAS
CSCD
北大核心
1989年第6期431-433,共3页
Chinese Journal of Cancer
