摘要
目的:评价利巴韦林三种给药途径治疗急性上呼吸道感染的临床疗效。方法:255例婴幼儿急性上呼吸道感染随机分为利巴韦林肌肉注射组、静脉给药组、滴鼻给药组,在综合治疗基础上加用利巴韦林,分别给予肌肉注射、静脉给药、鼻腔给药。结果:肌注显效率52.7%,总有效率77.7%;静脉给药显效率58.3%,总有效率90.2%;滴鼻显效率59.5%,总有效率91.0%。结论:利巴韦林滴鼻安全、有效、经济,因此在使用利巴林治疗病毒性急性上呼吸道感染时首选鼻腔滴入。
Objective： To evaluate the clinical effects of ribavirin administrated in three ways on acute upper respiratory infection in infants. Methods： 255 cases treated with ribavirin were randomly separated into three groups, each with a different administrative way： intramuscular injection, intravenous infusion or nose drops. Results： The effective rate was 52.7% in the group of ribavifin given by intramuscular injection and the total effective rate was 77.7%; the effective rate was 58.3% in the group of ribavifin given by intervenous infusion and the total effective rate was 90.2%; the effective rate was 59.5% in the group of fibavirin given in the way of nose drops and the total effective rate was 91%, both the highest. Conclusions： Ribavirin is safe, effective and economic while administrated in the way of nose drops. So nose drop is the first choice in treatment of acute upper respiratory infection with ribavifin.
出处
《儿科药学杂志》
CAS
2006年第2期28-29,共2页
Journal of Pediatric Pharmacy
关键词
利巴韦林
上呼吸道感染
婴幼儿
Ribavirin
Upper respiratory infection
Infants
