摘要
目的:探讨静脉丙种球蛋白(IVIG)对小儿病毒性心肌炎(VMC)的临床疗效及其免疫干预作用。方法:40例VMC患儿随机分为两组:对照组给予常规治疗,治疗组在常规治疗基础上给予IVIG治疗,观察治疗前后两组患儿CK-mB、cTnI、心电图及IL-6水平变化。结果:治疗后治疗组与对照组比较,CK-mB、cTnI、IL-6水平明显降低,心电图恢复正常百分率高,差异具有统计学意义(P均<0.05)。结论:IVIG对VMC心肌细胞具有保护作用,较常规治疗效果显著。
Objective： To explore chnic and immunologic effect of intravenous immunoglobulin （WIG） on children with viral myocarditis （VMC）. Methods： 40 cases with VMC were randomly divided into 2 groups： the control group were treated with ordinary regimen, treatment group treated with IVIG besides ordinary regimen. Cardiac enzyme（CK-mB）, troponine I（cTnI）, electrocardiography （ECG） and serum interleuckine 6 （IL-6） were determined before and after the treatment in all patients. Results： Compared with the control group, the level of CK-mB, cTnI, IL-6 significantly decreased in treatment group, ECG improved （P 〈 0.05） for more patients. Conclusions： IVIG have protective function to cardiomyocyte of children with VMC, and it＇s better than routine treatment.
出处
《儿科药学杂志》
CAS
2006年第2期14-15,共2页
Journal of Pediatric Pharmacy
