摘要
目的设计一种在不破坏虹膜形态结构和正常功能的前提下能用于虹膜组织力学特性及瞳孔阻滞力定量分析的仿真装置。方法用不锈钢制作瞳孔阻滞力仿真装置,用负压吸附虹膜,体外模拟瞳孔阻滞现象;依据连通器原理制作加压装置,模拟前后房压强差对虹膜整体进行加压。结果用此装置可以体外模拟完全瞳孔阻滞现象,经过动物试验获得的实验模型与临床现象相近,可以实现定量瞳孔阻滞力作用下的虹膜生物力学特性参量的测量。结论此装置是一种用于虹膜特性分析和瞳孔阻滞力定量分析的理想装置,实验给出了一种适用面较宽的小力学量、大曲率准球状腔体类生物软组织力学特性研究的实验方法。
Objective So far all the quantitative research of the pupil - blacking force and the iris dynamical property is very few because it is very difficult to realize the measurement of the dynamical property of soft tissues. We designed a device for measuring biomechanical properties of iris tissue and pupil-blocking force without destroying the structure and function of iris. Methods A pupil-blocking stimulating device was designed and made of stainless steel. Negative pressure was used to suck the iris in order to stimulate the pupil-blocking phenomena. A loading apparatus was designed according to the principle of connective tube to stimulate different pressure between the anterior and posterior chamber and to load the pressure on the whole iris tissue. Results The new device could be used to stimulate the pupil-blocking phenomena in vitro. The animal research was proved that the results were consistent with the clinical observation and it could be use to measure the iris＇ biomechanical property with the pupil-blocking force quantitatively. Conclusion The device is proved to be an ideal device for measuring biomechanical properties of iris tissue and pupil-blocking force quantitatively.
出处
《眼科研究》
CSCD
北大核心
2006年第2期206-208,共3页
Chinese Ophthalmic Research
基金
国家自然科学基金项目资助(30270356)
