期刊文献+

胃黏膜活检401例临床及病理分析 被引量:1

Clinical and Pathological Analysis of 401 Cases by Mucosa Biopsy
暂未订购
导出
摘要 目的 探讨儿童慢性胃炎的临床及病理特点及其与幽门螺杆菌(Hp)感染的关系。方法对401例临床有明显消化道症状但诊断未明者,男249例,女152例,行胃镜检查,均于胃窦部取1~2块黏膜组织行病理活检,随机抽取100例标本行Giemsa染色行Hp定性检测。结果儿童慢性胃炎主要以慢性轻-中度浅表性炎为主;儿童胃黏膜Hp感染以慢性炎症为主,其中慢性中-重度浅表性胃炎的检出率明显高于慢性轻度浅表性胃炎(X^2=7.61 P〈0.01)。结论儿童上消化道的疾病以炎症病变为主,Hp感染与胃溃疡及胃癌等疾病关系密切。 Objective To explore the clinical and pathological feature of pediatric chronic gastritis and whether gastritics in children related to hericobacter pylori(Hp). Methods Retrospective analysis the result of 401 children with gastroendosopy and 100 species with Hp detected were performed. Results Superficial gastritis form mild to moderate was the mainly pathologic change in pediatric chronic gastritis, chronic inflammation was the mainly change in pediatric Hp infection, and the detected rate of chronic superficial gastritis from mo-derate to heavy was significantly higher than mild(X^2=7.61 P 〈0.01 ). Conclusions The inflammation is mainly expression in children with upper digestive tract disease. Hp infection has very close association with gastric ulcer and gastric cancer.
出处 《实用儿科临床杂志》 CAS CSCD 北大核心 2006年第7期424-425,共2页 Journal of Applied Clinical Pediatrics
关键词 胃炎 螺杆菌 幽门 儿童 gastritis helicobacter pylori child
  • 相关文献

参考文献7

二级参考文献46

  • 1闫慧敏.小儿胃炎的诊断治疗进展[J].实用儿科临床杂志,2005,20(3):195-197. 被引量:16
  • 2胡余绍,吴国祥,刘建红.病毒性肝炎临床与病理的关系[J].实用儿科临床杂志,1996,11(1):29-30. 被引量:1
  • 3萧树东主编.江绍基胃肠病学:第一版[M].上海:上海科学技术出版社,2000.358.
  • 4Trevisani L. Evaluation of a new enzyme immunoassay for detecting helicobacter pylori in feces: a prospective pilot study[J]. Am J Gastroenterol, 1999,94 (7): 1830.
  • 5Elitsut Y, Neace C,Werthammer MC, et al. Prevalence of CagA, VacA antibodies in symptomatic and asymptomatic children with Helicobacter pylori infection[J ]. Hwelicobacter, 1999,4:100 - 105.
  • 6Leunk RD,Johnson PT,David BC,et al. Cytotoxin activity in brothculture filtrates of campylobacter pylori[J ]. J Med Microbiol, 1998,26:93- 95.
  • 7Cover TL,Dooley CP,Blaser MJ. Characterization of human serologic response to proteins in Helicobacter pylori broth culture supernatants with vacuolizing cytotoxin activity[J ]. Infect Immun, 1999,58: 603- 607.
  • 8Marchetti M. Development of a mouse model of Helicobacter pylori infection that mimics human disease[J]. Sience,1995,267:1655-1658.
  • 9Kim JW,Chung KS. Serum gastm and pepsinogen Ⅰ , Ⅱ concentrations in children with Helicobacter pylori infection: the role of CagA and VacA[J]. Yonsei MedJ, 1998,39:159- 165.
  • 10Tee W, Lambert JR, Dwyer B. Cytotoxin prodaction by helicobacter pylori from patients with upper gastrointestinal diseases[J ]. J Clin Microbiol, 1995,33:1203 - 1205.

共引文献43

同被引文献7

引证文献1

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部