摘要
目的:探讨术前化疗结合放疗治疗炎性乳腺癌的疗效。方法:采用环磷酰胺(CTX),吡柔比星(THP-ADM),氟脲嘧啶(5-FU)或CTX、甲氨喋呤(MTX)、5-FU化疗治疗21例炎性乳腺癌,每21天重复治疗。结果:全部病例随访5年以上,随访率100%。总有效率85.7%,3年、5年生存率为42.9%、23.8%。结论:炎性乳腺癌预后差,经术前化疗、放疗结合局部治疗可取得较好疗效。
Objective： To observe the effect of preoperative chemo-radiotherapy for inflammatory breast cancer. Methods： Twenty-one patients with inflammatory breast carcinoma were treated with a combined-modality approach. The protocol included chemotherapy consisted of cyclophosphamide, pirarubicin and 5-fluorouracil or cyclophosphamide, amothopterm and 5-fluorouracil. The same infusion schedule was repeated on day 21, total 3-4 cycles, then radiotherapy. Results： All patients were followed up at more than 5 years. The follow-up rate was 100.00%. The 3-year and 5-year survival rate were 42.9% and 23.8% respectively. Conclusion： Use of combined-modality treatment is recommended as a standard of care for inflammatory breast carcinoma.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2006年第7期384-385,共2页
Chinese Journal of Clinical Oncology
关键词
炎性乳腺癌
化学治疗
放射治疗
手术治疗
Inflammatory breast carcinoma Chemotherapy Radiotherapy Surgery
