摘要
目的探讨影响胆管癌围手术期死亡的危险因素。方法对6 2例胆管癌手术患者的临床资料进行回顾性研究。用Logistic回归法分析影响围手术期死亡的危险因素。对每一指标行单因素分析,筛选出P<0.1的自变量方可进入多因素分析。结果单因素分析显示影响围手术期死亡的可能因素有7个,即年龄、术前总胆红素、γ-GT、白(清)蛋白、肝功能分级、肿瘤分期、术前合并症;多因素分析显示显著影响围手术期死亡的危险因素有3个,按影响大小依次为年龄、肿瘤分期和γ-GT。结论高龄、高γ-GT水平和肿瘤分期晚增加胆管癌围手术期死亡的风险。
Objective To investigate the risk factors that affect the perioperative mortality in cholangiocarcinoma. Methods The clinical data of sixty two patients with cholangiocarcinoma who underwent operation were reviewed retrospectively. Logistic regression test was used in the perioperative mortality study. Before multivariate analysis, each parameter was evaluated with univariate analysis to define whether it was of statistical significance （ P 〈 0. 1 ） or not. Then the parameters with statistical significance were entered for further multivariate analysis. Results Univariate analysis showed 7 factors that might influence the perioperative mortality, included age, preoperative total bilirubin, γ-GT, albumin, tumour stage, liver function classification, and preoperative concomitant diseases. In multivariate analysis, results showed that 3 factors significantly influenced the perioperative mortality, which in order of significance were age, tumour stage, and γ-GT. Conclusions Aging, high γ-GT and late tumour stage are the risk factors, which can increase the perioperative mortality in cholangiocarcinoma.
出处
《中国普通外科杂志》
CAS
CSCD
2006年第3期173-176,共4页
China Journal of General Surgery
