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犊牛前胸腺素α基因的克隆及表达载体的构建和鉴定 被引量：1

Advances in study on chalk brood
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作者 李红梅 魏艳丽 任艳 智庆文 张凤英 王少杰 杨合同 张显升
机构地区 山东省科学院生物研究所山东省应用微生物重点实验室
出处 《中兽医医药杂志》 2006年第2期40-43,共4页 Journal of Traditional Chinese Veterinary Medicine
基金 山东省优秀中青年科学家科研奖励基金(03BS144)
关键词 胸腺素Α1 表达载体 鉴定 构建 克隆 基因 犊牛 白细胞介素 免疫系统 补体C3
分类号 Q782 [生物学—分子生物学] S823.85 [农业科学—畜牧学]
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参考文献8

  • 1邱磊,郭葆玉,苗红,道书艳,张冉,袁鹏群,杨旭.胸腺素а原的生物学活性及基因表达谱芯片分析[J].第二军医大学学报,2002,23(6):639-642. 被引量：3
  • 2Baxevanis C N,Spanakos G,Voutsas I F,et al.Increased generation of autologous tumor-reactive lymphocytes by anti-CD3 monoclonal antibody and prothymosin alpha[J].Cancer Immunol Immuno ther,1999,48 (2-3):71 ～ 84.
  • 3Goldstein A L,Low T L,McAdoo M,et al.Thymosinal apha1:Isolation and sequence analysis of an immunologically active thymic polypeptide[J].Proc Natl Acad Sci,1997,74:72 ～ 76.
  • 4Karetsou Z,Martic G,Tavoulari S,et al.Prothymosin alpha associates with the oncoprotein SET and is involved in chromatin decondensation[J].FEBS Lett,2004,19 (3):496 ～ 500.
  • 5Goldstein A L,Slater F D.White A.Preparation,assay,and partial purification of a thymic lymphocytopoietic factor (thymosin)[J].Proc Natl Acad Sci,1996,56:1010.
  • 6Vareli K,Frangou-Lazaridis M.Prothymosin alpha is localized in mitotic spindle during mitosis[J].Biol Cell,2004,96 (6):421 ～ 428.
  • 7Dosil M,Freire M,Gomez-Marquez J.Tissue-specific and differential expression of prothymosin alpha gene during rat development[J].FEBS Lett,1990,269(2):373 ～ 6.
  • 8Yang C H,Murti A,Baker S J,et al.Interferon induces the interaction of prothymosin-alpha with STAT3 and resuits in the nuclear translocation of the complex[J].Exp Cell Res,2004,298(1):197 ～ 206.

二级参考文献2

共引文献2

同被引文献19

  • 1HARITOS A A, GOODALL G J, HORECKER B L. Prothy-mosin alpha:isolation and properties of the major immunoreac tive form of thymosin alpha 1 in rat thymus[J]. Proc Natl Acad Sci USA, 1984,81(4): 1008-1011.
  • 2PAN Lu-xing, HARITOS A A, WIDEMANN J,et al. Human prothymosin alpha: Amino acid sequence and immunologic properties[J]. Arch Biochem Biophys, 1986,250(1): 197-201.
  • 3SHIAU A L,CHU C Y,SU W C,et al. Vaccination with the glycoprotein D gene of pseudorabies virus delivered by non pathogenic Escherichia coli elicits protective immune response [J]. Vaccine, 2001,19(23/24):3277-3284.
  • 4GARBIN F,ECKERT K,IMMENSCHUH P,et al. Prothymo sin alpha effects, in vitro, on the antitumor and cytokine pro duction of blood monocytes from colorectal tumor patients[J]. Int J Immunopharmacol , 1997,19(6) : 323-332.
  • 5BAXEVANIS C N, RECLOS G J, PAPAMICHAIL M, et al. Prothymosin alpha restores the depressed autologous and allo-geneic mixed lymphocyte responses in patients with systemic lupus erythematosus[J]. Immunopharmacol Immunotoxicol , 1987,9(4) :429-440.
  • 6MOSOIAN A, TEIXEIRA A, HIGH A A,et al. Novel function of prothymosin alpha as a potent inhibitor of human immunod- eficiency virus type 1 gene expression in primary macrophages [J]. J Virol, 2006,80 (18): 9200-9206.
  • 7SHIAU A L,CHEN Y L,LIAO C Y,et al. Prothymosin alpha enhances protective immune response induced by oral DNA vaccination against pseudorabies delivered by Salmonella choleraesuis[J]. Vaccine,2001,19(28/29):3947-3956.
  • 8SKOPELITI M, VOUTSAS I F, KLIMENTZOU P, et al. The immunologically active site of prothymosin a is located at the carboxy-terminus of the polypeptide. Evaluation of its in vitro effects in cancer patients[J]. Cancer Immunol, Immun, 2006, 55(10) : 1247-1257.
  • 9MOODY T W, LEYTON J, ZIA F, et a l. Thymosin al is chemopreventive for lung adenoma formation in A/J mice[J]. Cancer Lett, 2000,155 (2): 121-127.
  • 10ESCHENFELDT W H,BERGER S L. The human prothymosin alpha gene is polymorphic and induced upon growth stimu lation: evidence using a cloned cDNA[J]. Proc Natl Acad Sci USA, 1986,83(24): 9403-9407.

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中兽医医药杂志
2006年 第2期

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