地氯雷他定和盐酸西替利嗪治疗慢性荨麻疹临床对比观察被引量：7

Observation on the therapeutic effects of desloratadine on chronic idiopathic urticaria

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摘要目的:观察地氯雷他定治疗慢性特发性荨麻疹的临床疗效。方法:采用随机对照方法,用地氯雷他定和盐酸西替利嗪对慢性荨麻疹进行随机临床对比观察。结果:共观察患者87例,地氯雷他定组44例,盐酸西替利嗪组43例,地氯雷他定组的痊愈率和有效率分别为40.91%和84.09%,盐酸西替利嗪组的痊愈率和有效率分别为39.53%和86.05%,两组间比较在疗效,症状积分差异均无显著性(P>0.05)。结论:地氯雷他定治疗慢性荨麻疹安全有效,其疗效与盐酸西替利嗪相似。 ObjectiveTo observe the effect of desloratadine in the treatment ot chronic idiopathic urticaria. Methods A randomized parallel-controlled clinical trial was conducted in 87 subjects, 44 cases in desloratadine group, and 43 in cetirizine group. All patients took the drugs for 14 days. Results The therapeutic effective rate and cure rate of desloratadine were 84.09 % and 40.91%, and those of cetirizine were 86. 05% and 39. 53% respectively, Their therapeutic effects showed no statistical difference between the two groups （P〉0.05） Conclusion It is suggested that desloratatine is an effective drug in the treatment of chronic idiopathic urticaria. Its effect is similar to that of cetirizine.

作者刘恩让张书岭刘姝丽

机构地区深圳市第二人民医院皮肤科

出处《实用诊断与治疗杂志》 2006年第4期246-247,共2页 Journal of Practical Diagnosis and Therapy

关键词荨麻疹慢性特发性地氯雷他定盐酸西替利嗪 Urticaria idiopathic chronic desloratadine cetirizine

分类号 R758.24 [医药卫生—皮肤病学与性病学]

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参考文献7

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