摘要
对１９７８年１０月～１９９４年１２月间的５２例大肠息肉癌变进行了回顾性临床、内镜及病理分析，癌变率４．２７％，其患病率随年龄增长而显著增加，５０岁以上组最多见，占６５．３％。其中，以绒毛状腺瘤、混合腺癌癌变率较高，二者间无差异（Ｐ＞０．０５），管状腺癌较低，与前二者差异明显（Ｐ＜０．０１），并发现１例炎性息肉癌变。直径＞２．０ｃｍ，息肉癌变率明显高于２．０ｃｍ以下者（Ｐ＜０．０１）。息肉基底愈宽愈短，癌变率愈高。大部分癌变息肉均有形态学改变。探讨了大肠癌的组织发生，息肉癌变因素及息肉癌变的早期诊断，早期防治的方法。
From Oct.1978 to Dec.1994,1219 cases of large intestine polyps were found by endoscopic examination and 52 cases of them(4. 27%) were diagnosed as polyps showing canceration.In the latter cases,the canceration were more frequent in senile patients,accounting for 65.3% of patients over 50 years of age. The canceration rate was higher in villous polyps (20. 4%) and mixed polyps(12. 2%),and it was lower in tubular polyps(3. 62% ).There was a significant statistical difference between the third and the first two groups (P<0. 01).It was also found that the canceration rate was higher in polyps which was more than 2cm in diametrer than in those with less than 2cm in diameter (P<0. 01).The broader and shorter the pedicle of the polys was,the higher the canceration rate of the polyps would be.Endoscopic examination and resection are helpful in the prevention of the canceration of colon polyp.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1996年第8期545-548,共4页
Chinese Journal of Clinical Oncology
