摘要
目的:半暗带的定义随着检测手段的发展而不断更新,总结半暗带的影像学研究进展及各种研究半暗带影像学方法的优势;探讨脑出血周边半暗带的存在依据。资料来源:应用计算机检索Medline1995-01/2005-05关于半暗带的文章。检索词“intracerebralhemorrhage,infarct,penumbra,MRI”并限定文章的语种类为English。同时利用计算机检索中国期刊全文数据库1995-01/2005-05的相关文章,限定文章语言种类为中文,检索词“脑出血,半暗带,磁共振”。资料选择:对资料进行初审,纳入标准:①关于半暗带的定义的研究发展。②半暗带的影像学研究。③脑出血周边半暗带的相关研究。排除标准:排除重复性研究。资料提炼:共收集到符合上述要求的文献若干篇,排除重复性研究。阅读文献并再查阅相关文献。资料综合:半暗带的多数研究是针对缺血性卒中,人们通过磁共振,正电子发射断层扫描,动态灌注CT方法进行了大量的动物及临床实验研究。但对脑出血周边半暗带是否存在尚有争议,且研究有限。结论:半暗带在一定时间内是可以挽救的,是一个“动态”和“取决于时间”的概念。进一步深化脑梗死和急性脑出血血肿周边影像学研究,将会为临床最佳治疗效果提供依据。
OBJECTIVE： To summarize the development of the penumbra and the superiority of various, and explore the existence of the penumbra around the bematoma. The definition of penumbra renews with the improvement of detecting means.
DATA SOURCES： The relevant articles on penumbra published between January 1995 and May 2005 were searched for in Medline database with the key words of＂intracerebral hemorrhage, infarct, penumbra, MRI＂ in English. Similarly, the relevant articles between January 1995 and May 2005 were searched for in China Journal Full-text Database in Chinese with the key words of＂intracerebral hemorrhage, penumbra, MRI＂.
STUDY SELECTION： The literatures about penumbra were selected primarily. Inclusive criteria： （1）The development on the definition of the penumbra. （2）The research in the penumbra on the sereenage. （3）The study on the penumbra around the hematma. Exclusive criteria： Repetitive researches were excluded.
DATA EXTRACTION： There were many literatures in accordance with the above-mentioned criteria, and the articles with repetitive research were excluded, and then read literatures and look up more related reviews.
DATA SYNTHESIS： Most of the researches on penumbra are ischemic stroke, and a large number of animal and clinical experiments were conducted with the method of magnetic resonance imaging （MRI）, position emission tomography （PET） and dynamic CT peffusion imaging. But whether the penumbra around the hematoma does exist or not has been disputed for a long time and the research on which is limited.
CONCLUSION： The penumbra that is the concept of dynamic state and limited time can be saved in a certain time. Further research on cerebral infarction and sereenage of acute cerebral hemorrhage around the hematoma can provide evidences for optimal therapeutic efficacy in clinic.
出处
《中国临床康复》
CSCD
北大核心
2006年第14期144-146,共3页
Chinese Journal of Clinical Rehabilitation
