摘要
目的探讨癫发作和抗癫药物治疗对催乳素(PRL)分泌的影响。方法采用放射免疫法(RIA)检测49例患儿癫发作期间及抗癫药物治疗后血清PRL水平。结果癫发作后血清PRL水平要较正常对照组明显升高;癫发作类型和血清PRL水平升高之间具有明显的相关性;各种抗癫药物对血清PRL水平的影响不同。结论癫发作和抗癫药物治疗均明显影响垂体PRL的分泌功能。
Objective To discuss the effect of seizures and anticonvulsants on proactin （PRL） secretion. Methods The level of serum PRL was measured by radioimmunoassay in 49 patients after epileptic seizures and anticonvulsant treatment. Results The level of serum PRL in epileptic patients was markedly higher than that of the controls. The rise of serum PRL levels was correlated significantly with the types of epileptic seizures. The level of serum PRL was changed by the different anticonvulsant drugs. Conclusion Epileptic seizures and anticonvulsant treatment may affect the secrel;ion of PRL in the pituitary.
出处
《中国小儿急救医学》
CAS
2006年第2期116-118,共3页
Chinese Pediatric Emergency Medicine
关键词
癫痫
抗癫痫药
催乳素
放射免疫法
Epilepsy
Anticonvulsants
Prolactin
Radioimmunoassay
