摘要
目的:回顾分析钼靶X线诊断假阴性病例与真阳性病例之间的差异,了解X线假阴性病人的特点。方法:通过分析1988～1989年天津医科大学肿瘤医院外科治疗、均经病理证实431例女性原发乳腺癌,比较96例钼靶X线假阴性病例与335例真阳性病例之间临床、病理及预后的差异。结果:与真阳性组相比(1)假阴性组发病年龄低(43.2±1.66)岁对(49.1±1.10)岁。(2)肿块小(3.1±0.36)cm对(3.7±0.20)cm。(3)浸润性导管癌比例多(29.6%对16.8%)。(4)单纯癌比例少(58.0%对68.6%)。(5)雌激素受体阳性率低(63.3%对84.9%)。(6)假阴性组腋窝淋巴结转移数目3个以下者多(60.4%对40.6%)。(7)假阴性组雌激素受体阳性者10年生存率比真阳性组低(53.5%对69.7%)。结论:钼靶假阴性的乳腺癌病人年轻、乳腺致密、肿瘤较小且缺乏细胞成分,虽然其临床表现较早,但预后差。临床有可疑之处时,应当积极诊治,以免病程延误。
Objective： To study retrospectively the difference between the female breast cancer with false-negative mammograms and with true-positive mammograms in order to know the characters of false-negatents. Methods： There were 431 cases of primary female breast cancer that received operation from 1988 to 1989 in the Department of Breast, Tianjin Cancer Hospital. Among these cases, there were 96 cases with false-negative mammograms and 335 true-positive cases. The clinical-pathologicalmammographic difference between them was compared. Results： Comparing with true-positive group（l） the onset-age of false-negative patients is lower （43.2±1.66 years vs 49.1±1.10 years）.（2）the size of tumor is smaller（3.1±0.36 cm vs 3.7±0.20 cm）.（3）infihrating duct carcinoma is more（29.6% vs 16.8%）.（4） carcinoma simplex is less （58.0% vs 68.6%）.（5）the positive rate of estrogen receptor is lower （63.3% vs 84.9%）.（6）the group of false-negative patients whose number of positive axillary lymph nodes are less than three are more（60.4% vs 40.6%）.（7）ten-year survival rate of false-negative patients whose estrogen receptor is positive is lower than true-positive patients （53.5% vs 69.7%）. Conclusion： Breast cancer with false-negative mammograms had younger onset-age, dense gland tissue, small tumor, and less cancer cell component. Because of little clinical signs and worse prognosis, the suspected patients should be examined actively to be diagnosed early and not to be delayed.
出处
《天津医科大学学报》
2006年第1期90-93,96,共5页
Journal of Tianjin Medical University
