摘要
目的:通过无创的方法测量踝臂指数(ABI),评价其作为老年男性冠心病危险因素的地位和作用。方法:随机选取符合实验设计条件的61例老年男性(>65岁)冠心病患者(30例)和非冠心病患者(31例)作为患者组和对照组,分别测量踝臂指数(ABI)和其它相关变量。采用t检验、二分类logistic回归等方法进行统计处理。结果:经统计学处理两组踝臂指数(ABI)比较,患者组比对照组踝臂指数低(t=47.664,P<0.05)具有统计学意义;logistic回归显示,ABI(OR=0.533,95%CI,0.399～1.521,P<0.05)与脉压(OR=1.367,95%CI,0.536～1.998,P<0.05)、C反应蛋白(OR=1.701,95%CI,1.363～1.952,P<0.05)等传统的冠心病危险因素一同进入回归方程。结论:本实验设计从根本上排除了高血脂和糖尿病对血管造成危害而引起的混杂因素,从而更能说明ABI的降低可能是冠心病的独立危险因素之一。
Objective： To make noninvasive measures of ankle-braehial index （ABI） to assess its role in older age male patients with coronary heart disease （CHD）. Methods： A total of 61 male patients ehoosed ramdomly in older age （〉65 years） were separated into 2 groups as patient group （n=30） and control group （n=31） by certain rules and measured ABI and some other values respectively. The data are analyzed by t-test and logistic regression. Results： The ABI is different significantly in two groups in statistics and the value in CHD patients is lower than non-CHD patients（t=47.664, P〈0.05）. Logistic regression shows that the ABI （OR=0.533, 95%CI, 0.399-1.521, P〈0.05）is selected into regression equation as a risk factor of CHD equivalent to the traditional risk factor pulse pressure（OR=l.367, 95% CI, 0.536-1.998, P〈0.05） and C-reactive protein （OR =1.701, 95%CI, 1.363-1.952, P〈0.05）. Conclusion： It is much powerful to prove that the decreased-ABI is one of the risk factors of CHD, because from the beginning we excluded the negative effect of hyperlipemia and diabetes on vessels.
出处
《天津医科大学学报》
2006年第1期65-67,70,共4页
Journal of Tianjin Medical University
关键词
踝臂指数
冠心病
危险因素
老年
男性
Ankle-brachial index
Coronary heart disease
Risk factor
