摘要
目的:观察生血康治疗特发性血小板减少性紫癜(ITP)患者骨髓巨核细胞的变化．方法:治疗组30 例,采用生血康(蒙药制剂)3g,每日3次口服,对照组30例,强的松1 mg／(kg．d),每日1次顿服(或每日分3 次口服)．两组均以6周为一个疗程,6周后强的松逐减量．并观察骨髓象的变化．结果:治疗组治疗后原、幼巨核和颗粒型巨核细胞明显减少,产板型巨核细胞明显增多,与对照组比较具有显著性差异(P<0．05)．结论: 生血康具有促进骨髓巨核细胞的成熟,使原、幼巨核和颗粒型巨核细胞减少,产板型巨核细胞增多致使升高血小板之功能．
Objective： To observe megakaryocyte ＇ s changes of patients with idiopathic thrombocy- topenic purpura （ITP） treated with Shengxuekang （SXK, Mongolian medicine）. Methods： Treatment group had 30 patients. We treated the patients with SXK, 3g three times a day. Control group had 30 patients. We treated the patients with prednisone, lmg/kg/d,one time a day. The treatment course of both groups lasted six weeks. We gradually reduced the dosage of prednisone six weeks later. Results： In treatment group, megakaryoblast, promegakaryocyte and granular megakaryocyte decreased. At the same time plateelet - producing megakaryocyte increased. The difference between the two groups is significant （p〈 0.05）. Conclusion： It shows SXK has the function that increases platelet through promoting maturity of megakaryocyte, decreases the amount of megakaryoblast and promegakaryocyte and increases the amount of platelet - producing megakaryocyte.
出处
《内蒙古民族大学学报（自然科学版）》
2006年第1期78-79,共2页
Journal of Inner Mongolia Minzu University：Natural Sciences
