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人肝细胞 L-02/聚丙烯杂化界面的初步研究:肝细胞球形聚集体培养 被引量：1

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摘要 生物人工肝（bioartificial liver，BAL）在肝功能衰竭中的治疗价值已得到肯定，大量高活性的人肝细胞是细胞型体外BAL支持系统的核心原材料。球形聚集体是一种立体、高密度、高活性培养肝细胞的方法，但操作较复杂。我们采用生物材料表面接枝功能化学基团的方法，对人肝细胞L-02／聚丙烯杂化界面进行了研究，并通过简单的静止培养实现了肝细胞的球形聚集体培养方式，极大的简化了既往的肝细胞球形聚集体培养方法。
作者 彭承宏 韩宝三 高长有 马祖伟 王涌 刘宏 赵之明 唐喆
机构地区 浙江大学医学院附属二院普外科 浙江大学高分子复合材料研究所
出处 《中华肝胆外科杂志》 CAS CSCD 2006年第3期210-212,共3页 Chinese Journal of Hepatobiliary Surgery
基金 国家自然科学基金资助(基金编号:20074031)
关键词 人肝细胞L-02 聚集体培养 聚丙烯 球形 杂化 步研究 生物人工肝 liver 肝功能衰竭 培养肝细胞
分类号 R329.2 [医药卫生—人体解剖和组织胚胎学]
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共引文献37

同被引文献26

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中华肝胆外科杂志
2006年 第3期

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