摘要
勃起功能障碍是中老年男性常见多发病,近几年来其治疗的进展比较快,也引起了广泛关注。目前常用的一线口服治疗药物包括西地那非、伐地那非和他达拉非,临床效果相似但各有其特点。二线治疗包括阴茎海绵体血管注射疗法和尿道内用药,但因使用时有侵袭性而受限。目前所有的治疗方法都存在着不同程度的不良反应,基因治疗可能是未来ED治疗的发展方向。
Erectile dysfunction (ED) is a common condition in men from 40 to 70 years of age, and during the last decades intensive research has highlighted clinical practice and public sectors. The development of Sildenafil, Vardenafil and Tadalafil have made the first class of agents capable of treating ED with convenient oral administration available. In the past years intracavemosal and intraurethral agents have been developed, but their clinical use was limited due to its invasiveness, and with high discontinuation rates. Gene therapy will be an effective method in future.
出处
《基础医学与临床》
CSCD
北大核心
2006年第3期241-245,共5页
Basic and Clinical Medicine
关键词
勃起功能障碍
药物
治疗
erectile dysfunction
drug
therapy