摘要
目的探讨抗结核药诱发肝损害(即药物性肝损害drug-inducedliverinjury,DILL)的发病情况及特点。方法回顾分析近10年来669例结核病在使用抗结核药中诱发的69例(10.3%)肝损害的临床资料,观察与分析肝损害情况。结果该组肝损治愈缓解率达98.6%(68/69)、死亡率1.4%(1/69)。结论抗结核药物诱发肝损害应引起重视,对HBVM阳性者选用抗结核药时要慎重。
[Objective] To obserue the effect of Drug-induced liverinjury （DILL）. [Methods] The liver functions of 69 cases in 669 cases （from 1995 to 2005） were retrospectively analyzed. [Result] The total effect was 98.6% （68/69） on after treatment. The death rate was 1.4%（1/69）. [Conclusion] The Drag-induced liver injury must he regarded. The choose of antituberculotic medicine should be an attention to patients with HBVM positive.
出处
《中国医学工程》
2006年第1期53-54,57,共3页
China Medical Engineering
关键词
肺结核抗结核药
肝损害
pulmonary tuberculosis
antituberculotie liver injury
