摘要
目的观察低剂量螺内酯治疗充血性心力衰竭（CHF）的临床疗效。方法100例CHF患者随机分成螺内酯组52例，对照组48例，螺内酯组在常规治疗的基础上加用螺内酯20-40mg/d，连续应用8周以上。结果螺内酯组与对照组比较左室射血分数、每搏输出量和临床疗效差异有显著性（P〈0．05）。结论螺内酯治疗充血性心力衰竭有较好的临床疗效，可改善心功能和临床症状，降低病死率。
Objective To evaluate the clinical efficacy of low-dose spironolactone treatment on congestive heart failure （CHF） .Methods 52 patients received low-dose spironolactone 20-40 mg a day for 8 weeks, with the routine treatment. Results Compared with those in control group, EF volume, stroke volume in spironolactone treatment group were significantly increased. In Addition, the clinical manifestations were also improved in spironolactone treatment group （ P 〈 0.05）. Conclusion The low-dose spironolactone is effective in treating congestive heart failure, which could improve clinical manifestation and the heart function, which also could decrease the mortality.
出处
《河北医药》
CAS
2006年第3期176-177,共2页
Hebei Medical Journal
关键词
充血性心力衰竭
螺内酯
心衰治疗
congestive heart failure
spironolactone
therapy for heart failure
