摘要
本文观察了４４例老年冠心病患者及３０例健康老年人（对照组）血脂水平及丙二醛和超氧化物歧化酶的血清含量。结果显示，除胆固醇外其余各指标两组间均有显著差异。冠心病组丙二醛明显高于对照组，而超氧化物歧化酶则明显低于对照组。多元回归分析表明，低密度脂蛋白胆固醇与丙二醛呈显著正相关（ｒ＝０．５１３９，Ｐ＜０．００１）。高密度脂蛋白胆固醇与超氧化物歧化酶呈显著正相关（ｒ＝０．５７０２，Ｐ＜０．００１）。提示老年冠心病患者高脂血症与脂质过氧化间有一定关系。
The levels of serum lipoprotein (a)[Lp(a)], apolipoprotein A1 (Apo A1), apolipoprotein B (Apo B), high-density lipoprotein cholesterol (HDLC), low-density lipoprotein cholesterol (LDLC), total cholesterol (TC), triglyceride(TG),malondialdehyde ( MDA ) and superoxide dismutase (SOD) were measured in 30 old healthy subjects and 44 old patients with coronary heart disease (CHD).Lp (a), Apo B, LDLC and MDA were higher, and Apo A1, HDLC and SOD were lower in CHD patients than in controls (P<0. 05 or P<0. 01). Multiple regression analysis revealed that levels of LDLC correlated signiflcantly with level of MDA (r=0. 5139,P<0.001 ) and level of HDLC correlated significantly with serum SOD activity (r=0. 5702,P<0. 001). The results suggested that hyperlipemia in old CHD patients was closer relationship to lipids peroxidation.
出处
《中国动脉硬化杂志》
CAS
CSCD
1996年第1期58-61,共4页
Chinese Journal of Arteriosclerosis
关键词
冠心病
血清脂质
过氧化脂质
老年人
Coronary heart disease
Serun lipids
Lipids peroxidation
