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他卡西醇治疗白癜风的临床观察 被引量:2

A clinical trial of tacalcitol for the treatment of vitiligo
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摘要 目的:观察他卡西醇外用治疗白癜风的疗效及安全性。方法:采用单盲、自身对照的方法,对100例白癜风患者的自身对称或相邻皮损分别外用他卡西醇、维生素E霜,1个月观察1次疗效,连续观察3个月。结果:治疗侧皮损有效率为83.7%,对照侧为41.3%,治疗侧色素再生时间早于对照侧。结论:他卡西醇治疗白癜风安全、有效。 Objective To assess the safety and efficacy of topical tacalcitol for the treatment of vitiligo. Methods 100 patients with vitiligo were enrolled in a single-blind, auto-controlled clinical trial.Lesions were selected to be either tacalcitol or vitamine E ointment,and then examined monthly. Patients were treated for 3 months. Results Effective rate of treatment with tacalcitol is 83.7%, effective rate in the control lesions is 41.3%.The repigmentions was initiated earlier in the lesions treated with tacalcitol than those with vitamine E ointment. Conclusion Tacalcitol ointment is an effective alternative therapy for vitiligo and is a well-tolerated drug.
出处 《中国美容医学》 CAS 2006年第3期315-316,共2页 Chinese Journal of Aesthetic Medicine
关键词 白癜风 他卡西醇 vitiligo tacalcitol
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参考文献7

  • 1Parsad D,Saini R,Verma N.Combination of PUVAsol and topical calcipotriol in vitiligo[J].Dermatology,1998,197(2):167-170.
  • 2全国中西医结合皮肤性病学会色素性皮肤病学组.白癜风的临床分型及疗效标准[J].临床皮肤科杂志,1995,24(5):282-282.
  • 3Lepe V,Moncada B,Castanedo-Cazares JP,et al.A double-blind randomized triai of 0.1% tacrolimus vs0.05% clobetasol for the treatment of childhood vitiligo[J].Arch Dermatol,2003,139(5):581-585.
  • 4Ameen M,Exarchou V,Chu AC.Topical calcipotriol as monotherapy and in combination with psoralen plus ultraviolet A in the treatment of vitiligo[J].Br J Dermatol,2001,145(3):476-479.
  • 5汤芦艳,傅雯雯,吴文育,项蕾红,郑志忠.他卡西醇软膏治疗白癜风的自身对照观察[J].临床皮肤科杂志,2005,34(2):119-120. 被引量:5
  • 6Schallreuter KU,Wood JM,Pittelkow MR,et al.Increased monoamine oxidase A activity in the epidermis of patients with vitiligo[J].Arch Dermatol Res,1996,288(1):14-18.
  • 7王家壁.皮肤性病治疗与检测进展精要[M].北京:清华大学出版社,2005:226.

二级参考文献9

  • 1全国中西医结合皮肤性病学会色素病学组.白癜风临床分型及疗效标准(草案).临床皮肤科杂志,1995,24(5):282-282.
  • 2Parsad D, Saini R, Verma N. Combination of PUVAsol and topical calcipotriol in vitiligo[J]. Dermatology, 1998, 197(2): 167-170.
  • 3Parsad D, Saini R, Nagpal R. Calcipotriol in vitiligo: a preliminary study[J]. Pediatr Dermatol, 1999, 16(4): 317-320.
  • 4Lepe V, Moncada B, Castanedo-Cazares JP, et al. A doubleblind randomized trial of 0.1% tacrolimus vs 0.05% clobetasol for the treatment of childhood vitiligo[J]. Arch Dermatol, 2003,139(5): 581-585.
  • 5Schallreuter-Wood KU, Pittelkow MR, Swanson NN. Defective calcium transport in vitiliginous melanocytes [J]. Arch Dermatol Res, 1996, 288(1): 11-13.
  • 6Schallreuter KU, Pittelkow MP. Defective calcium uptake in keratinocyte cell cultures from vitiliginous skin [J]. Arch Dermatol Res, 1988, 280(3): 137-139.
  • 7Tomita Y, Torinuki W, Tagami H. Stimulation of human melanocytes by vitamin D3 possibly mediates skin pigmentation after sun exposure[J]. J Invest Dermatol, 1988, 90(6): 882-884.
  • 8Ameen M, Exarchou V, Chu AC. Topical calcipotriol as monotherapy and in combination with psoralen plus ultraviolet A in the treatment of vitiligo[J]. Br J Dermatol, 2001, 145(3): 476-479.
  • 9Chiaverini C, Passeron T, Ortonne JP. Treatment of vitiligo by topical calcipotriol[J]. J Eur Acad Dermatol Venereol, 2002, 16(2): 137-138.

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