摘要
目的探讨血清甘胆酸（ＣＧ）水平对肝硬变肝功能分级的价值。方法按Ｃｈｉｌｄ分级将１０３例肝炎后肝硬变（ＬＣ）患者分为Ａ，Ｂ，Ｃ３级，采用ＲＩＡ分别检测其空腹血清ＣＧ水平。结果肝硬变Ｂ（ｎ＝４２，７１．５±２７．４μｍｏｌ／Ｌ）和Ｃ（ｎ＝３５，６８．３±２５．９μｍｏｌ／Ｌ）二组ＣＧ含量显著高于Ａ组（ｎ＝２６，４８．９±２４．２μｍｏｌ／Ｌ）（Ｐ＜０．０１）；Ｂ和Ｃ组间ＣＧ含量无差异（Ｐ＞０．０５）。
AIMS To evaluate the significance of glycocholic acid (CG) in serum on grading of liver function in patients with liver cirrhosis. METHODS Liver One hundred and three cirrhosis (n=103) were divided into group A,B and C according to Child's classification. The level of serum CG in fasting state was measured by using RIA. RESULTS Concentration of glycocholic acid in serum in group B(n=42, 71.5±27.4μmol/L) and C(n=35, 68.3±25.9μmol/L)were higher than that in group A(n=26, 48.9±24.2μmol/L)(P<0.01), but there was no significant difference between group B and C(P>0.05). CONCLUSIONS The changes of serum CG can reflect the severity of liver function.
关键词
肝硬变
肝功能
甘胆酸
血清
glycocholic acid blood liver cirrhosis/blood liver physiopathology radiommunoassay
