摘要
目的:观察苦宝降脂胶囊对高脂血症小鼠的血脂及营养性肥胖模型大鼠的体重、体内脂肪重量、指数的影响。方法:采用实验性高脂血症小鼠,检测血清总胆固醇(TC);用营养性肥胖模型大鼠,检测血清总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白(HDL-C)及检测营养性肥胖模型大鼠的体重、体内脂肪重量、Lee’s指数。结果:苦宝降脂胶囊能显著降低实验性高脂血症小鼠的TC,对营养性肥胖模型大鼠的体重具有明显的抑制作用,明显减轻体内脂肪重量和显著降低Lee’s指数,明显降低血清TC、TG,提高HDL-C水平。结论:苦宝降脂胶囊具有降脂减肥,调节血脂的作用。
Objective： To observe the effects of Kubao Jiangzhi Capsule on the blood lipid of the mice with hyperlipidemia and body weight, fat weight, blood lipid in the rat model with nutritional obesity. Mothods： The expermental hyperlipidemic mice was used to test the serum TC; The rat with nutritional obesity was used to test the serum TC、TG、HDL-C and body weight, body fat weight, Lee＇s index. Results： Kubao Jiangzhi Capsule could decrease the serum TC in the expermental hyperlipidemic mice. It could inhibit body weight, decrease body fat weight and Lee＇s index, decrease the serum TC、TG, increase HDL-C in the rat model with nutritional obesity. Conclusion： Kubao Jiangzhi Capsule has the antihyperlipidemia action.
出处
《中国实验方剂学杂志》
CAS
2006年第3期51-53,共3页
Chinese Journal of Experimental Traditional Medical Formulae
关键词
苦宝降脂胶囊
降脂
调节血脂作用
Kubao Jiangzhi Capsule
antihyperlipidemia
regulating blood lipid action
