摘要
目的研究连续输注多巴胺用于重度二尖瓣狭窄患者的麻醉诱导中维持循环功能稳定的安全性。方法重度二尖瓣狭窄行二尖瓣置换患者20例,随机分为2组。Ⅰ组单纯用咪达唑仑、芬太尼和哌库溴铵诱导;Ⅱ组诱导前静脉用输注泵输入多巴胺3μg.kg-1.min-1,再用咪达唑仑、芬太尼和哌库溴铵诱导。在诱导前、给药后、插管后即刻、插管后2、5、10min分别监测血压、心率、血氧饱和度等。结果多巴胺组患者麻醉诱导后血压下降不明显,心率减慢,气管插管后血压、心率变化不大。对照组麻醉诱导后血压、心率明显下降和减慢;而气管插管后血压、心率升高和加快明显。结论麻醉诱导前静脉输注小剂量多巴胺维持有助于保持患者血流动力学的稳定。
Purpose The study attempted to assess the safety of the infusion of dopamine for anesthesia induction in the patients with the severe mitral stenosis. Methods Twenty patients undergo ing elective mitral valve replacement were studied （10 patients in each group）. Anesthesia was induced with fentanyl, midazolam, pipecuromium. Small dose dopamine 3 μg·kg^-1·min^-1 was used before anesthesia induction in dopamine group, control group use none. BP, HR and SpO2 was measured at before induction,after administion, after intubated,2 min,5 min and 10 min after intubaed. Results In dopamine group BP insignificantly decreased, HR significantly decresased, but BP,HR was no significantly changed after intubation. In control group BP, HR significantly decreased after induction, significantly increased after intubation. Conclusions The small dose dopamine before anesthesia induction is conribute to hemodynamic stability.
出处
《复旦学报（医学版）》
CAS
CSCD
北大核心
2006年第2期260-261,F0004,共3页
Fudan University Journal of Medical Sciences
关键词
重度二尖瓣狭窄
多巴胺
麻醉诱导
severe mitral stenosis
dopamine
anesthesia induction
