摘要
目的:分析松果体区病变MRI表现并探索1H-MRS及DWI对于鉴别松果体区病变的作用。材料和方法:松果体区病变患者共33例,其中男27例,女6例,年龄7～51岁,平均年龄21.3±10.3岁。全部33例都作了MRISE-T1WI,FSE-T2WI,PDWI,FLAIR及增强MRI成像检查。其中7例患者术前行1H-MRS和DWI检查。结果:大多松果体区病变有其特征的外形、信号强度及强化方式;MRS:2例生殖细胞瘤Ch/NAA(2.06和2.11)、LL/Cr(0.83和4.2);2例成熟畸胎瘤LL/Cr(7.3和9.64),测不到Ch和NAA;2例星形细胞瘤Ch/NAA(3.55和3.53);1例松果体母细胞瘤Ch/NAA4.70。ADC值:生殖细胞瘤7.48×10-4和6.48×10-4;畸胎瘤2.03×10-3和3.57×10-3;星形细胞瘤1.91×10-3和1.35×10-3;松果体母细胞瘤9.14×10-4。结论:病变的外形特征、信号强度及强化方式对于松果体区病变的诊断最有帮助。1H-MRS及DWI在某种程度上对于鉴别诊断有帮助。
Purpose： To analyze characteristic MR Imaging of pineal region diseases and to explore the value of DWI and ^1H- MRS in differential diagnosis. Materials and Methods： 33 patients with pineal region diseases proved by pathology presented at 7 to 51 years old （mean 21.3 - 10.3 Y.O.）, 6 were females and 27 males.All of them underwent MRI SE - T1WI, FSE - T2WI, PDWI, FLAIR and post - contrasted MR scan. Furthermore, MRS and DWI before operation were achieved in seven patients. Results： Most pineal region diseases have their tipical morphology, singal intensity and enhancement style. On MRS, germinoma showed Ch/NAA （2.06 and 2.11）, LL/Cr （0.83 and 4.2）, mature teratomas LL/Cr（7.3 and 9.64）, without Ch and NAA and astrocytoma Ch/ NAA （3.55 and 3.93）; pineoblastoma Ch/ NAA 4.7. ADC value of germinoma was 7.48×10^-4 and 6.48×10^-4 ; mature teratoma 2.03×10^-.3 and 3.57×10^-3; astrocytoma 1.91 ×10^-3 and 1.35 ×10^-3 ; pineoblastoma 9.14 ×10^-4 . Conclusion： Change in morphologic features, singal intensity and enhancement style is the most helpful variable for the differential diagnosis of pineal region diseases. To some extent DWI and ^1H - MRS imaging enable distinction among them.
出处
《中国医学计算机成像杂志》
CSCD
2006年第1期58-61,共4页
Chinese Computed Medical Imaging
基金
2005年复旦青年科学基金资助
编号JKf151007。
关键词
松果体
磁共振成像
磁共振波谱成像
Pineal body Magnetic resonance imaging Magnetic resonance spectroscopy
