摘要
采用PCR—ASO方法，对日本筑波大学101名中国汉族留学人员的DNA样品进行了原纤维蛋白－1基因（FBN1）第27内含子G／A多态性测定。结果发现，A等位基因频率为0．5396G等位基因频率为0．4604。与Tynan等人报道的数据（A和G等位基因的频率分别为0．1675和0．8325）相比，有非常显著差异（P＜0.01），提示两样本间有不同的遗传背景。
The G / A polymorphisms in intron 27 of fibrillin-1 gene in 101 Chinese Hans who were studying and working in University of Tsukuba, Japan were analyzed with PCR-ASO method. The frequencies of A and G alleles, were 0.5396 and 0.4604 respectively. In a population sample reported by Tynan the frequency of A allele was 0.1675 while that of G alle1e was 0. 8325. The distribution of G / A polymorphism was significantly different betwecn the two population sample (P<0. 01), suggesting different genetic backgrounds.
出处
《遗传》
CAS
CSCD
北大核心
1996年第4期12-14,共3页
Hereditas（Beijing)
