摘要
目的合成苄普地尔衍生物。方法以异丙醇、环氧氯丙烷、哌啶为起始原料,反应中间体经二氯亚砜氯化后,与取代苯胺等缩合得到目标化合物。结果设计并合成了6个苄普地尔衍生物。结论6个衍生物均经红外光谱、核磁共振氢谱和质谱确证结构。
From readily available starting materials, isopropanol, epichlorohydrin and piperidine, six bepridil derivatives were symhesized via chlorination with SOCl2 and condensation with substituted anilines. The structures of the target compounds were elucidated on the basis of spectral data （IR,^1H NMR and MS）.
出处
《广东药学院学报》
CAS
2006年第1期36-38,共3页
Academic Journal of Guangdong College of Pharmacy
关键词
多药抗药性
苄普地尔衍生物
合成
muhidrug resistance
bepridil derivatives
synthesis
