摘要
目的探讨女性高催乳素(PRL)血症的原因和治疗。方法对60例高催乳素血症患者临床资料进行回顾性分析。结果垂体腺瘤22例(36.7%),其中2例行手术治疗,20例予溴隐亭治疗。空蝶鞍l例(1.7%),予手术治疗。药物所致7例(11.7%),其中5例停止服药后3个月恢复正常月经。伴多囊卵巢综合症3例(5.0%),其中1例予促排卵治疗妊娠。甲状腺功能减退2例(3.3%),予口服甲状腺素治疗4月后月经恢复正常。特发性25例(41.7%),其中5例无临床症状者予定期观察,20例伴临床症状者予溴隐亭治疗。60例高催乳素血症患者采用溴隐亭治疗者40例,均取得良好效果。结论高催乳素血症应针对病因进行治疗。溴隐亭仍是治疗高催乳素血症的首选药物。
Objective To study the pathogenesis and treatment of hyperprolactinemia. Methods 60 patients of hyperprolactinemia who came to clinic from 1988 to 2004 were retrospectively analyzed. Results 22 patients （36.7%） were caused by pituitary gland carcinoma, of which 2 cases with treatment of surgery and 20 cases with treatment of bromocryvtine. 1 patient （1.7%） was due to empty sella syndrome and treated with surgery. 7 patients （11.7% ） were caused by pharmaceuticals, of which 5 cases restored normal menstruation after non-taking such pharmaceuticals. 3 patients （5.0%） accompanied with polycystic ovary syndrome. After treatment with induced ovulation 1 case was pregnant. 2 patients（2.3%） were due to thyroid function deficiency and treated with thyroxin. 25 patients had no definite pathogenesis, of which 5 patients underwent non-treatment and were observed regularly, 20 patients were treated with bromocryptine. Totally 40 patients were treated with bromocryptine and abtained good curative effect. Conclusion Patients with hyperprolactinemia should be treated respectively according to different pathogenesis, bromocryptine remains the optimal medicine in the treatment of hyperprolactinemia.
出处
《中国现代医药杂志》
2005年第6期47-48,共2页
Modern Medicine Journal of China
关键词
高催乳素血症
治疗
Hyperprolactinemia
Treatment
