摘要
目的观察胰岛素泵注治疗对危重病高血糖状态的控制效果及对并发症的影响。方法对31例血糖高于16.6mmol/L的危重患者,在末梢血糖监测下用胰岛素持续泵注治疗,泵注量按血糖情况调节。结果治疗后血糖、血钠、血浆晶体渗透压分别为(10.16±2.25)mmol/L、(135.47±10.12)mmol/L、(301.24±10.07)mmol/L,与治疗前的(34.5±11.6)mmol/L、(146.71±12.25)mmol/L、(340.87±16.56)mmol/L相比有显著差异(P<0.05),治疗后尿糖转阴、酮症酸中毒纠正、神志改善;血钾从4.83±1.49mmol/L降至3.51±1.06mmol/L,平均动脉压(MAP)稍有升高,但无统计学意义(P>0.05)。结论胰岛素泵注治疗危重病高血糖快捷、平稳、治疗效果满意,较少引起低血糖、低血钾、脑水肿等,值得临床推广使用。
Objective To observe the effect of insulin pump therapy on hyperglycosemia in severe patients. Methods 31 severe patients were involved in study, whose blood glucose （BG） was over 16.6mmol/L. Insulin pump was used to adjust the BG under peripheral blood glucose. Results Post-treatment BG, serum sodium, plasma crystal osmotic pressure were （10.16±2.25）mmol/L, （135.47±10.12）mmol/L, （301.24±10.07）mmol/L, and statistical analysis showed there were significant difference （P〈0.05） to contrast pretreatment BG （34.5±11.6）mmolfL, serum sodium（146.71±12.25）mmol/L, plasma crystal osmotic pressure （340.87±16.56）mmol/L. Post-treatment urine glucose （UGlu） became negative, ketoacidosis was rectifyed, consciousness was improved, serum potassium declined from 4.83±1.49mmol/L to 3.51±1.06mmol/L. Not with standing the mean arterial pressure （MAP） was slightly increased, there was no significant difference（P〉0.05）. Conclusion Insulin pump therapy on hyperglycosemia in severe patients were fast, lasting and efficacious. There was lower incidence in hypoglocemia, hypokalemic, cerebral edema etc, so it is great value of clinic generalization.
出处
《中国现代医药杂志》
2005年第6期44-46,共3页
Modern Medicine Journal of China
关键词
危重病
高血糖
胰岛素治疗
Severe disease
Hyperglycosemia
Insulin treatment （IT）
