摘要
目的探讨无创正压通气(NIPPV)在COPD并SAS急性加重期及稳定期治疗的效果评价。方法通过对COPD并SAS患者急性加重期给予无创正压通气(NIPPV)治疗,观察疗效。稳定期根据采取的治疗措施,分别分为单纯氧疗组和氧疗加NIPPV组,分别在每个患者出院后3月复查血气分析,并追踪其在出院后2年内再入院次数。结果无创正压通气(NIPPV)治疗COPD并SAS患者急性加重期,血气分析提示pH值、氧分压及二氧化碳分压均较治疗前有不同程度的改善,P<0.05,稳定期氧疗加NIPPV组与单纯氧疗组比较在二氧化碳分压及pH值方面均有改善,P<0.05,同时两年内再入院次数减少,人均住院费用下降,P<0.05。结论在COPD并SAS急性加重期给予NIPPV治疗,能有效改善缺氧及高碳酸血症,稳定期的继续治疗,较单纯氧疗能有效减少患者的再住院次数,降低住院费用,同时降低了COPD并SAS患者的死亡率。
Objective To study the effects of NIPPV for patients with COPD and SAS in acute exacerbation period and stable period. Methods Observed the effects of NIPPV in patients with COPD and SAS. Patients with stable COPD and SAS were divided into two groups by the way of different therapy： patients with only oxygen supply; patients with both oxygen and NIPPV supply. Blood gas test was repeated three months later after hospitalization of each patient, and the frequency of each patients＇ rehospitalization were followed in two years after hospital discharge. Results After NIPPV therapy to patients with COPD and SAS in acute exacerbation period, the blood gas test indicated that the patients＇ pH, PO2, PCO2 had been improved in some extents, P〈0.05. Compared to the group with only oxygen therapy, PCO2 and pH had been improved in the group with both NIPPV and oxygen therapy, P〈0.05, the frequency of rehospitalization had been decreased and the cost of hopitalization had been reduced, P〈0.05. Conclusion NIPPV used for patients with COPD and SAS can improve their hypoxemia and hypercarbia efficiently. Compared to those with stable COPD and SAS only with oxygen therapy, the frequency of rehospitalization, the cost of hospitalization and mortality are reduced among patients who with beth oxygen and NIPPV therapy.
出处
《中国现代医药杂志》
2005年第6期3-5,共3页
Modern Medicine Journal of China
