摘要
目的探讨超声造影对肝转移癌的诊断价值。方法对43例肝转移癌病灶（原发癌分别为腺癌32例，鳞癌9例，恶性间质细胞瘤1例，多发性骨髓瘤1例）行超声造影（CEUS）检查，观察其开始增强时间、动脉灌注特点及增强类型，并与其原发肿瘤的病理细胞类型比较。观察造影前、后动脉相病灶的血流变化，对血流进行分级比较。CEUS动脉相（0-40s）、门脉相（41～120s）观察病灶增强类型，延迟相（120S以后）观察全肝病灶数目并与增强CT比较。结果CEUS动脉相肝转移癌Ⅲ～Ⅳ级血流的病灶数目较造影前明显增加（P〈0．05）；肝转移癌病灶动脉灌注、增强类型表现多样，与其原发肿瘤的病理细胞类型比较缺乏特异性；CEUS肝转移病灶增强类型不同于增强CT，且在延迟相较增强CT能发现更多新病灶。结论CEUS对肝转移癌具有重要诊断价值。
Objective To explore the diagnostic value of contrast-enhanced ultrasound （CEUS） in metastatic liver tumors. Methods Forty-three patients with metastatic liver tumors （the pathologic cell types of primary tumors including 32 adenocarcinoma,9 squamous cell carcinoma, 1 malignant mesenchyma cell tumor, 1 multiple myeloma） were examed with pulse-inversion harmonic imaging after an intravenous administration of SonoVue. The initiatory enhancement time, the characterization of arterial phase perfusion and the enhancement types of the lesions were observed and compared with pathologic cell types of the primary tumors. The flow of lesions were compared and classified into four grades separately before and after CEUS. The enhancement types of the lesions were observed at arterial phase （0-40 s） and portal vein phase （41-120 s）, and the total number of metastatic lesions in every patient were observed at late phase （after 120 s）,the enhancement types and the total numberenhancement of metastatic lesions in every patient were compared with contrast-enhanced CT. Results After CEUS the number of Ⅲ～Ⅳ grade flow lesions was significantly more than before CEUS （ P 〈0. 05）. The types of metastatic liver tumors were various, scarcing specificity compared with pathologic cell types of the primary tumors. At arterial phase the enhancement types of metastatic lesions detected with CEUS partially differed from contrast-enhanced CT,and more metastatic lesions were observed with CEUS than contrast-enhanced CT at late phase. Conclusions CEUS plays an important role in dignosis of metastatic liver tumors.
出处
《中华超声影像学杂志》
CSCD
2006年第3期198-201,共4页
Chinese Journal of Ultrasonography
基金
河北省科技厅重点科技攻关项目(05276101D-69)
关键词
超声检查
造影剂
肝肿瘤
肿瘤转移
Ultrasonography
Contrast media
Liver neoplasms
Neoplasm metastasis
