摘要
目的:观察灯盏细辛对眼压已控制的青光眼患者视网膜微循环的影响。方法:将眼压已控制的36例青光眼患者随机分为两组,双盲法让患者口服安慰剂或美尔瑞,服用3个疗程,每个疗程2mo,共6mo,用海德堡视网膜血流仪(Heidbergretinalflowmetry,HRF)检查视神经乳头和视盘旁视网膜各4个点血流,分别与基线值进行比较。结果:服药后4,6mo,试验组视盘和视盘旁视网膜Vol,Vel,Flw与基线比较,视盘与视盘旁视网膜微循环明显改善。结论:口服美尔瑞(灯盏细辛)能够明显改善眼压已控制的青光眼患者视盘和视盘旁视网膜微循环,这种作用与疗程有关。
AIM: To determine the effect of erigeron breviscapus hand-mazz (EBHM) on optic nerve head (ONH) and peripapillary blood flow by Heidelberg retina flowmeter (HRF).
METHODS: ONH and peripapillary retinal blood flow of 36 glaucomatous patients with controlled intraocular pressure were measured by HRF before and 2, 4 and 6mo after two pills (EBHM or placebo) were given thrice a day for 6mo in a double blind way. RESULTS: In the volume, flow and velocity of ONH and peripapillary retinal blood flow, there were significant changes from the baseline values at 4 and 6mo after taking EBHM.
CONCLUSION: EBHM can increase the volume, velocity and flow of the ONH and peripapillary retinal blood in glaucomatous patients with intraocular pressure controlled; this effect is related to the course.
出处
《国际眼科杂志》
CAS
2006年第1期107-109,共3页
International Eye Science