摘要
目的探讨体外循环(CPB)预充液中不加白蛋白对瓣膜置换患者术后的影响。方法62例年龄<60岁体外循环下瓣膜置换患者,术前白蛋白均正常,随机分为预充蛋白组(A组,n=34)和不预充蛋白组(B组,n=28)。两组预充液均为复方乳酸钠林格液、706代血浆、5%碳酸氢钠、25%甘露醇,组间比较无显著性差异。A组预充白蛋白20g。比较两组术前、术后血清白蛋白水平,术后至次日7时白蛋白入量等。结果两组术前白蛋白水平、术后至次日7时白蛋白入量及7时的血清白蛋白水平均无显著性差异。结论术前非低蛋白的瓣膜置换患者,体外循环预充液中不加入白蛋白是安全的。
Objective To analyze and evaluate the effect addition of albumin to the extracorporeal circulation （CPB） in patients undergoing valve replacement. Methods 62 patients under 60 years of age, with the blood level of albumin nearly normal, undergoing mitral valve replacement or aortic valve replacement were randomly divided into two groups. In 34 patients albumin was added to the priming fluid of extraporeal circulation, and in 28 patients it was not. The preoperative and postoperative serum albumin levels, the duration of assisting ventilation, and the amount of albumin needed between the time of operation to 7 am of the first postoperative day were compared. In both groups the primary priming fluid consisted of balanced electrolyte solution, hydroxyethyl starch, 5% sodium bicarbonate, and 25% mannitol. Resdts All the indexes, including the preoperative level of albumin, the amount of albumin needed from operation to 7 am of the first postoperative day, and the albumin level at 7 am of the first postoperative day showed no notable differences. Conclusion For patients with no hypoalbuminemia, mitral valve replacement or aortic valve replacement is safe to withhold the addition of albumin to the priming fluid for CPB.
出处
《解放军医学杂志》
CAS
CSCD
北大核心
2006年第3期254-255,共2页
Medical Journal of Chinese People's Liberation Army
关键词
体外循环
白蛋白
心脏瓣膜假体植入
extracorporeal circulation
serum alburnin
heart valve prosthesis implantation
