摘要
Since the discovery of mast cells (MCs) in 1878, MCs have long been recognised to be the key effector cells in allergic reactions. However, little is known about their roles in defending microorganisms. In this review, the recent research progress in the roles of MCs, in the body defence against bacterial and viral infection, in pathogen recognition mechanisms and in inflammatory mediator release are discussed.
Since the discovery of mast cells （MCs） in 1878, MCs have long been recognised to be the key effector ceils in allergic reactions. However, little is known about their roles in defending microorganisms. In this review, the recent research progress in the roles of MCs, in the body defence against bacterial and viral infection, in pathogen recognition mechanisms and in inflammatory mediator release are discussed.
出处
《中国病理生理杂志》
CAS
CSCD
北大核心
2006年第3期607-611,共5页
Chinese Journal of Pathophysiology
基金
国家自然科学基金资助项目(No.30570813)
广东省自然科学基金资助项目(No.04106122)
关键词
肥大细胞
细菌感染
病毒
Mast cells
Bacterial infections
Viruses
