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脑局部孤立离断术治疗难治性癫痫 被引量:8

Focal cortex disconnection for the treatment of intractable epilepsy
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摘要 目的探讨脑局部孤立离断术的患者适应证、术前评估手段及手术疗效。方法分析 6名难治性癫痫患者的术前术后资料,对患者的评估手段、手术结果进行分析。结果 6名患者中, 随访9-15个月,5名发作消失,达到Engel Ⅰ级治疗,1名患者发作得到有效控制,发作频率减少 90%以上。1例患者出现头皮下积液,术后2个月复查时,头皮下积液完全消失。结论在手术适应证的要求下,综合多种术前评估方法,尤其是脑功能的准确测定可以使脑局部孤立离断术成为一种安全有效的手术。 Objective To figure out indications of focal brain disconnection, preoperative evaluations and surgical outcome. Methods The data of 6 surgical cases with intractable epilepsy were analyzed. The preoperative evaluations and surgical outcome were analyzed. Result Six patients with surgical treatment were followed up for 9 to 15 months. Five of 6 patients got seizure free after surgical treatment and one patient got 90% reduction of seizure after operation. One patient developed subcutaneous CSF accumulation and relieved 2 months later. No patients developed neurological deficit. Conclusion With certain indications and careful multiple preoperative evaluations, the focal brain disconnection for seizure control is safe and effective.
出处 《中华神经外科杂志》 CSCD 北大核心 2006年第3期147-150,共4页 Chinese Journal of Neurosurgery
关键词 难治性癫痫 神经外科 手术治疗 脑局部孤立离断术 适应证 Intractable epilepsy Neurosurgery Surgery
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参考文献5

  • 1Rasmussen T.hemispherectomy for seizures revisited.Can J Neurol Sci,1983,10:71-78.
  • 2Van Wagenen WP,Herre RY.Surgical division of the commissural pathways in the corpus callosum:relation to spread of an epileptic attack.Arch Neurol Psychiatry,1940,44:740-759.
  • 3刘智良,徐如祥,张新伟,周谷兰.胼胝体前部离断联合多种术式治疗难治性全面发作性癫痫[J].广东医学,2002,23(6):588-590. 被引量:3
  • 4Morrell F,Whisler WW,Smith MC.Multiple subpial transaction in Rusmussen's encephalitis.In:Andermann F,ed.Chronic encephalitis and epilepsy Rasmussen's Syndrome.Boston:Butterworth-Heinemann,1991,219-233.
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二级参考文献2

  • 1解学孔 唐丽瓯 等.癫痫病学[M].北京:人民卫生出版社,1997.297.
  • 2谭启富 刘承基 李文智 等.胼胝体前部切开术治疗难治性癫痫初步报告.中华神经外科杂志,1985,1(1):23-25.

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