摘要
目的评价头孢他啶治疗老年慢性阻塞性肺疾病(COPD)合并急性下呼吸道细菌性感染的临床疗效和安全性。方法将65例老年COPD伴急性下呼吸道细菌性感染患者分成两组,泰得欣组32例,采用泰得欣4～6g/d,每日2～3次,静脉滴注；头孢哌酮组33例,给予头孢哌酮2．0g,每日两次,静脉滴注；两组疗程均为7～10d。结果泰得欣组治愈率为68．8％,有效率为90．6％,细菌清除率为91．2％；头孢哌酮组治愈率为60．6％,有效率为87．9％,细菌清除率为90．3％；两组比较差异无显著性(P>0．05)。结论泰得欣治疗老年COPD伴急性下呼吸道细菌性感染疗效确切、使用安全。
Objective To evaluate the efficacy and safety of intravenous ceftazidime in the treatment of lower respiratory tract infection in the elderly patients with chronic Obstructive pulmonary disease （COPD）. Methods Sixty - five patients were randonly divided into two groups .32 Patients in treatment group（n = 32） were treated with ceftazidime 4 - 6g, iv, bid - rid for 7 - 10 days. 33 Patients in control group were given. Cefoperazone 3.0g, iv, hid for 7 - 10 days （n= 33）. Results In cefiazidime group, the cute rate was 68.6%. The effective rate was 90.6% . and bacterial eradication rate was 91.2% . In Ccfoperazonc group, the cure rate was 60.6% . The effective rate was 87.9% . and bacterial eradication rate was 90.3% . There was no statistically significant difference between the two groups. Conclusion Ceflazidime is effective and safe for treatment of lower respiratory tract infections in the elderly patients with COPD.
出处
《中国热带医学》
CAS
2006年第3期489-490,共2页
China Tropical Medicine
关键词
头孢他啶
下呼吸道感染
慢性阻塞性肺疾病
老年
Cefiazidime
Lower respiratory tract infection
Chrnoic obstructive pulmonary disease
Elderly
Cefoperazone
