摘要
目的：研究Ｐ物质（ＳＰ）和Ｐ物质受体（ＳＰＲ）在大鼠终纹床核（ＢＳＴ）各亚核内的分布．方法：正常雄性Ｓｐｒａｇｕｅ－Ｄａｗｌｅｙ大鼠６只，体重约２００～２５０ｇ．按ＡＢＣ法行ＳＰ和ＳＰＲ免疫组织化学染色；并应用图像分析仪对染色结果进行半定量分析．结果：ＢＳＴ各亚核内的ＳＰ及ＳＰＲ样免疫阳性反应有较明显的差异．结论：提示ＢＳＴ细胞构筑上具有非均一性，各亚核在功能上可能存在差异．
Objective:To study the distribution of substance P(SP)and substance P receptors(SPR)in the subnuclei of the bed nucleus of the stria terminalis(BST)in the rat.Metbods:Normal male Sprague-Dawley rat,200～250 g.SP and SPR staining by means of ABC immunohistochemistry,and the results were studied semi-quantitatively with an image analyser.Results:It was shown that the density of SP-and SPR positive immunoreactivity was obviously different in each subnucleus of the BST.Conclusion:The result suggests heterogeneity in cytoarchitecture of the BST and possible functional difference among the subnuclei of the BST.
出处
《第四军医大学学报》
1996年第2期144-146,共3页
Journal of the Fourth Military Medical University
关键词
终纹床核
P物质
受体
bed nucleus of the stria terminalis substance P receptors,neurokinin-1 immunohis-tochemistry image processing,computer-assisted rat
