摘要
对５０例重型颅脑损伤患者（ＧＣＳ３～８分）及５０例伤情与诊断和手术方式基本相似的另一组患者进行颅内压（ＩＣＰ）与脑灌注压（ＣＰＰ）连续监测对比研究，结果表明，监护组除８例ＩＣＰ压力＜２．００ｋＰａ，ＣＰＰ＞９．３３ｋＰａ外，余４２例均有不同程度ＩＣＰ增高与ＣＰＰ降低。这些患者分别为创伤性颅内血肿、广泛性脑挫裂伤、继发性脑水肿或脑肿胀等，均采取积极的手术及综合治疗，预后较好，死亡率为１４％。非监护组治疗方法与监护组相同，预后较差且并发症多，死亡率为２８％，认为，对重型颅脑损伤患者施行连续ＩＣＰ，ＣＰＰ监护，是降低并发症和死亡率，提高疗效的有力措施，具有重要的临床应用价值。
We compared and analysed the treatment results of two groups of patients.Group Ⅰ included 50 cases of severe brain injury with GCS 3～8,on whom continuous intracranial pressure(ICP)and cerebral perfusion pressure(CPP)monitoring was performed and Group Ⅱ included 50 cases of similar patients,on whom no continuous ICP monitoring was performed.In Group Ⅰ there were 8 cases with normal ICP(<2.0kPa),CPP(>9.33 kPa),and in the rest 42 cases,ICP was increased and CPP was reduced.After adequate intervention,including operation and drug treatment,patients in Group Ⅰ had good results,and the mortali-ty was 14%.Patients in Group Ⅱ received the same intervention based on clinical observations,but had rela-tively worse results,the mortality being up to 28%.The authors are of the opinion that continuous ICP and CPP monitoring for severe brain injury patients should be performed,this will help to find proper treatments and reduce mortality.This procedure has great clinical importance.
出处
《第四军医大学学报》
1996年第2期123-126,共4页
Journal of the Fourth Military Medical University
关键词
颅脑损伤
颅内压
脑灌注压
监护
severe brain injury intracranial pressure cerebral perfusion pressure custodial care
