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吸烟者血浆Ⅷ因子相关抗原和纤维蛋白原水平检测

MEASUREMENT OF PLASMA FACTOR Ⅷ RELATED ANTIGEN AND FIBRINOGEN IN 50 SMOKERS
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摘要 本文采用Luarell氏免疫火箭电泳法和免疫单扩散法,分别测定50名吸烟者血浆Ⅷ因子相关抗原(ⅧR·Ag)和纤维蛋白原(Fbg)的含量,结果发现吸烟者血浆中此两种蛋白的含量均有不同程度地增加,与对照组相比差异显著(P<0.01及P<0.02)。众所周知,ⅧR·Ag和Fbg是反映血液凝固性的重要指标,因此,本结果提示吸烟导致血液凝固性升高,可能是吸烟引起心血管损害的重要机理之一。 Contents of factor Ⅷ related antigen (Ⅷ R·Ag) and fibrinogen ( Fbg ) in human plasma in 50 smokers were measured by immu-noelectrophoresis rocket and immunomonodiffusion. It was found that plasma Ⅷ R·Ag and Fbg contents increased from 103.72% to 154.60% ( P<0.01), and from 91.36% to 111.36% ( P<0.02 ) respectively. The results suggest that the smoking of cigarettes is conducive to the development of blood coagulation, which may be one of the mechanisms associated with cardiovascular injury caused by smoking.
出处 《蚌埠医学院学报》 CAS 1990年第2期32-34,共3页 Journal of Bengbu Medical College
关键词 相关抗原 纤维蛋白原 心血管损害 factor Ⅶ related antigen fibrinogen smoking
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