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腹腔镜卵巢打孔术治疗难治性多囊卵巢综合征合并不孕 被引量:5

Laparoscopic treatment of polycystic ovarian syndrome with insulated needle cautery
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摘要 目的:探讨腹腔镜卵巢打孔术治疗难治性多囊卵巢综合征(PCOS)合并不孕的临床价值、适应证及机理。方法:对符合PCOS标准的不孕症47例采用腹腔镜电针双侧卵巢打孔术,观测术后排卵、妊娠、流产情况,比较手术前后血FSH,LH和T值的变化及月经情况的改变。结果:术后血清雄激素(T)及黄体生成激素(LH)明显下降,术后排卵率为85.1%。妊娠率为61.7%,早期流产率为10.3%,无1例发生卵巢过度刺激综合征(OHSS)。结论:腹腔镜卵巢打孔术可提高PCOS合并不孕患者的自然排卵率及对克罗米芬的敏感性,从而提高妊娠率,是PCOS不孕症特别是难治性PCOS患者恢复卵巢生理功能的有效手段,但应掌握手术时机和手术指征。术后3个月未妊娠者尽早采用促排卵药物以提高妊娠率。 Objective :To evaluate the clinical applying value,inclication and mechanism of insulated needle eautery laparoseopy for treatment of polycystic ovarian syndrome (PCOS)in clomiphene-resistant anovulatroy women. Methods:Forty-seven patients were clomiphene-resistant anovulatory with PCOS. Laparoscopic ovarian drilling use an insulated needle eantery. They were observed the changes of blood FSH, LH, T and the ovuatory rate, pregnancy rate, abortion rate. Results:The ovalation rate was 85.1%, the pregnancy rate was 61.7% ,the abortion rate was 10.3% ,the level of blood LH and T decreased apparently. Conclusions: Laparoseopie ovarian drilling is an effective alternative treament in clomiphene-resistant anovulatroy women with PCOS. The use of an insulated needle cantery is rapid effective, simple, safe, minimal invation and less adhesion.
出处 《腹腔镜外科杂志》 2006年第1期16-17,共2页 Journal of Laparoscopic Surgery
关键词 多囊卵巢综合征 不育 女性 腹腔镜 Polycystic ovary sndrome Infertility, female Laparoscopy
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参考文献2

  • 1Tozer AJ,Shawaf AI,Zosmer A,et al.Dose laparoscopic ovarian diathermy after the outcome of IVF-embryo transfer in women with polycystic ovarian syndrome?a retrospective comparative study[J].Hum Reprod,2001,16:91.
  • 2Li TC,Saravelos H,Chow MS,et al.Factors affecting the outcome of laparoscopic ovarian drilling for polycysitic ovarian syndrome in women with anovulatory infertility[J].Br J Obstet Gynaecol,1998,105:338.

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