摘要
脓毒症是引起危重病人死亡的常见原因,对于脓毒症的发生机制,凝血功能紊乱的研究日益受到关注。凝血、抗凝及纤溶系统的失衡,在脓毒症的发生、发展中扮演着重要角色。凝血因子与炎症介质相互促进,加快病情发展。本文将就脓毒症中凝血功能的改变及其对病情发展的影响进行概述。
Sepsis is the common reason for the death of critica illness patients. Coagulation disorders are being paid more and more attention in the pathogenesis of sepsis. Disequilibrium among coagulation, anticoagulation and fibrinolysis plays an important role in the occurence and development of sepsis. Interaction between coagulation factors and mediators of inflammation promotes with each other, which aggravates the severity of the disease. This article review s coagulation-associated changes in sepsis and its influence on the progression of sepsis.
出处
《医学综述》
2006年第5期296-298,共3页
Medical Recapitulate
关键词
脓毒症
凝血
炎症介质
Sepsis
Coagulation
Mediators of inflammation