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氯沙坦加杏丁注射液对糖尿病肾病的疗效观察 被引量：5

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摘要 目的:观察氯沙坦加杏丁注射液治疗糖尿病肾病的疗效。方法:将32例糖尿病肾病患者分为A、B两组,每组各16例。A组给予氯沙坦50mg口服,1次/d,杏丁注射液20mL+生理盐水100mL缓慢静脉滴注,1次/d。B组给予氯沙坦50mg口服,1次/d。疗程为12周。观察治疗前后24h尿蛋白(Tp/24h)、血肌酐(Scr)、空腹血糖(FBS)、血钾、平均动脉压(MBP)、总胆固醇(TC)、甘油三酯(TG)、血浆黏度、红细胞压积、血浆凝血酶时间(TT)。结果:两组治疗后Tp/24h、MBP均有明显下降;两组治疗前后Scr、血钾、FBS、红细胞压积均无明显变化;A组治疗后TC、TG、血浆黏度和TT明显下降,而B组无明显改变;治疗前后TC、TG、血浆黏度和TT的下降A组较B组明显,且差异有显著性。结论:氯沙坦联合杏丁注射液治疗糖尿病肾病,除了可以降尿蛋白、控制血压外,还具有降血脂,降低血液黏度,纠正血液高凝状态的作用,能有效延缓肾功能恶化。
作者 付艳燕 贾汝汉
机构地区 武汉大学人民医院肾内科
出处 《实用医学杂志》 CAS 2006年第5期580-581,共2页 The Journal of Practical Medicine
关键词 耱尿病肾病 氯沙坦 杏丁注射液
分类号 R692.9 [医药卫生—泌尿科学]
  • 相关文献

参考文献10

  • 1杨定平,贾汝汉,丁国华,姜诗琴.氯沙坦对早期糖尿病肾病大鼠的保护作用[J].医药导报,2004,23(9):615-618. 被引量：5
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二级参考文献15

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实用医学杂志
2006年 第5期

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