摘要
目的探讨气道内悬挂125Ⅰ粒子治疗中心型肺癌引起的气道狭窄和肺不张的方法和疗效。方法采用环甲膜穿刺、置管、气道内悬挂125Ⅰ放射性微粒子方法,对中心型肺癌进行持续近距离放疗。治疗观察时间3个月。结果21例患者中,气道狭窄CR 5例、PR 10例、AC 4例、PD 2例,CR+PR 15(72%)。并发颈部瘘口炎性肉芽组织增生、喉部不适、导管刺激性咳嗽各3例,血WBC下降低于正常2例,导丝在颈部折断1例。结论经环甲膜穿刺,气道内悬挂125Ⅰ粒子对于治疗肺癌引起气道狭窄和肺不张的方法简便、安全和有效。
Objective To evaluate the method and the efficacy of endobronchial brachytherapy to malignent airway stricture with ^125I implanted via cricothyroid membrane puncture and suspended in airway. Methods Central lung cancer had undergone endobronchial brathytherapy with ^125I implanted viacricothyroid membrane puncture and suspended in airway which was guided by X-rayor fiberoptic bronchoscopy. The treating time was three months. Results Of 21 cases, CR（airway stricture complete relief）, PR, AC, and PD were 5, 10, 4 and 2 respectively, CR ＋ PR was 15 （72 % ）. Complications such as inflammatory granuloma in neck, laryngeal malaise, irritating cough were just the same 3 patients; hypoleuko-cytosis and broken guidewire in neck were 2 and 1 respectively. Conclusion Endobronchial brachytherapy with ^125I implanted via cricothyroid membrane puncture and suspended in airway for malign airway stricture is simple, effective and safe.
出处
《实用临床医药杂志》
CAS
2006年第1期65-67,共3页
Journal of Clinical Medicine in Practice
基金
河北省卫生厅资助项目(04034)
关键词
^125I粒子
腔内放疗
肺癌
气道狭窄
^125I
endobronchial brachytherapy
lung cancer
airway stricure
