摘要
【目的】探讨急性胆囊炎炎症发作时间和炎症程度与肝功能损害的关系。【方法】将830例患者按炎症发作时问和炎症程度分为1，3d、4，7d、8d以上3组和轻、中、重3组，设100例患者（无肝胆疾病）为对照组，针对4项肝功能指标：胆红索（TBIL）、谷草转氨酶（AST）、谷丙转氨酶（ALT）和血浆白蛋白（ALB）与对照组两两比较统计学处理，代人u检验。【结果】炎症发作1。3d组除ALT显著差异外（P〈0．05）．TBIL、AST、ALB均无显著性差异（P〉0．05）；4-7d和8d以上组4项指标均有显著性差异（P〈0．05，P〈0．01）。炎症程度轻度组4项均无显著性差异（P〉0．05）。中重度组均有显著性差异（P〈0．05，P〈0．01）。【结论】急性胆囊炎炎症时间和炎症程度与肝功能损害成正相关，保肝、消炎、尽早手术切除胆囊是肝功能恢复的最好方法。
[Objective] To explore the relation between the time and the degree of inflammation in acute choleystitis and liver function damage. [Methods] According to the time of onset and degree of inflammation of acute cholecystitis, 830 cases of acute cholecystilis were divided into 1 - 3 d, 4 - 7 d, and over 8 d 3 groups and light, median and serious degree 3 groups. 100 cases of liver and bile duct diseases were set as control group. Four liver function indexes： TBIL, AST, ALT and ALB were determined and compared. [Remits] TBIL, AST and LAB in the 1 - 3 d group showed no marked difference （P 〉 0. 05）, but ALT showed remarkable difference （P 〈 0. 05）. Four indexes showed remarkable and most remarkable difference in the 4 - 7 d, and over 8 d group （ P 〈 0.05） or （ P 〈 0.01）. All four indexes showed no obvious difference in the light inflammation of the gallbladder group （ P 〉 0.05）, there were remarkable and most remarkable difference in the groups of median and serious inflammation of the gallbladder （ P 〈 0.05 or 〈 0.01 ）. [Conclusion] There is a positive relationship between the time of onset and the inflammation degree of acute cholecystitis and the damage of liver function, It is suggested that the best way for the recovery of liver function is liver protection, cantrol of inflammation and performing cholecystectomy in time.
出处
《武警医学院学报》
CAS
2006年第2期106-108,共3页
Acta Academiae Medicinae CPAPF
关键词
急性胆囊炎
肝功能
损害
Acute cholecystitis
Liver function
Damage
