摘要
目的探讨4～7岁哮喘患儿脉冲振荡肺功能（IOS）异常与正常值的分界点。方法选择正常患儿124例，发作期哮喘儿童160例。采用Mastscreen IOS肺功能仪进行IOS测定，计算IOS主要参数在不同预计值水平判断肺功能异常的敏感度与特异度。结果哮喘患儿IOS参数与正常儿童显著不同，以呼吸总阻抗（Zrs）≥115％正常预计值作为肺功能异常时，其对哮喘诊断的敏感度和特异度均为0．68；以总呼吸道黏性阻力（R5）≥115％正常预计值作为异常时，其敏感度和特异度则分别为0．61和0．63；而以电抗（X5）≥110％正常预计值作为异常时，其敏感度和特异度分别为0．84和0．81。结论对哮喘患儿进行IOS测试时，应将Zrs、R5≥115％正常预计值，X5≥110％正常预计值作为判断异常指标。
Objective To determine the cutoff point between normal and abnormal value of 4 7 years old asthmatic children with impulse oscillation system （IOS）. Methods IOS lung function was measured in 124 normal children and 160 asthmatic children with attack. The sensitivity and specificity to iudge ahnomality with IOS main parameters in different levels of predicted normal value was calculated. Results The value of IOC parameters between normal and asthmatic children was significantly different. The sensitivity and specificity were all 0.68 when total respiratory impedance （Zrs）≥115 % normal predicted was adopted as abnormality. The sensitivity and specificity were 0.61 and 0.63 when respiratory resistance at 5 Hz （ R5 ） ≥ 115 % normal predicted was adopted as abnormal; and the sensitivity and specificity_were 0,84 and 0, 81 when airway reactance at 5Hz （X5）≥110 % normal predicted was adopted as abnormal. Conclusion Zrs,R5≥115% normal predieted,X5≥110% normal predicted could be considered as abnormal.
出处
《实用儿科临床杂志》
CAS
CSCD
北大核心
2006年第4期206-207,共2页
Journal of Applied Clinical Pediatrics
关键词
儿童
哮喘
脉冲振荡
children
asthma
impulse oscillation system
