摘要
１９７７年４月至１９９３年１２月间共做肾移植８０１例，人／肾５年存活率７４．６４％／５３．０２％，对其中１２７例长期应用ＣｓＡ康复５年以上的肾移植受者作了临床研究，所有患者保持定期随访。研究表明：应改善病人术前全身状况，提高组织配型和取肾质量。慢性排斥是影响移植肾长期存活的主要因素，早期明确诊断，一周内及时调整免疫抑制剂用量是提高逆转率的关键。认为应重视肺部感染和ＣｓＡ肝毒性的防治。ＣｓＡ序贯性用药疗效可靠。强调定期随访是提高长期康复率的保证。
A survey of 127 renal graft recipients surviving more than 5 years with long term oral cyclosporin has been made.Preoperative promotion of general health,better typing and graft of high quality were important.Whereas,chronic rejection was a primary factor affecting long-term survival.Early diagnosis of the chronic rejection and readjustment of the immunosuppressives with in the first week might increase the reverse rate.Attention should be paid to pulmonary infection and cyclosporin A hepatotoxicity.Sequencial use of cyclosporin A has been effective and regular periodic follow-up was essential to long-term survival.
出处
《中华泌尿外科杂志》
CAS
CSCD
北大核心
1996年第1期8-10,共3页
Chinese Journal of Urology
