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厄多司坦辅助治疗放射性肺炎的临床观察 被引量:3

Clinical Study of Erdosteine in the Assistance Treatment of Radiation Pneumonitis
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摘要 目的评价厄多司坦辅助治疗肿瘤患者胸部放疗后并发放射性肺炎的临床疗效及其使用安全性。方法对照组20例放射性肺炎患者使用抗生素(左氧氟沙星)和激素(地塞米松)治疗;治疗组25例患者在对照组治疗方法的基础上再加厄多司坦0.6 g,口服,2次/d,疗程为2周。结果两组患者疗效间差别有显著性意义(P<0.05)。结论厄多司坦辅助治疗肿瘤患者胸部放疗后并发放射性肺炎安全有效。 Objective To observe the effect and safety of erdosteine in treating radiation pneumonitis after tumor sufferer's bust radiotherapy. Methods 20 patients of control group use the antibiotic and the hormone, 25 patients of treatment group add the erdosteine 0. 6 g, potid based on the control group. The period of treatment is two weeks. Results There was significant difference between the two groups ( P 〈 0. 05). Conclusion Erdosteine was effective and safety in assistance treating radiation pneumonitis after tumor sufferer's bust radiotherapy.
作者 夏德洪 奚蕾
出处 《中国全科医学》 CAS CSCD 2006年第4期328-329,共2页 Chinese General Practice
关键词 厄多司坦 辐射性肺炎 抗生素 激素 Erdosteine Radiation pneumonitis Antibiotic Hormone
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参考文献6

  • 1刘进,王选锭,刘富光,钮善福,周建英.厄多司坦胶囊对慢性支气管炎祛痰疗效的临床研究[J].中国临床药理学杂志,2002,18(1):26-29. 被引量:9
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二级参考文献5

  • 1[1]Olivieri D, Del Donno M, Casalini A,et al. Activity of erdosteine on mucociliary transport in patients affected by chronic bronchitis.Respiration, 1991 ;58:91~94.
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  • 5[5]Hosoe H, Kaise T, Ohmori K, et al. Mucolytic and antitussive effects of erdosteine. J Pharm Pharmacol, 1999;51:959~966.

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