摘要
我们应用组织化学和免疫组织化学技术对１３４例胆囊良恶性病变的各类化生及其化生与胆囊癌的关系进行研究。结果发现，胆囊粘膜上皮异型增生均发生在化生区内，且多数发生在肠上皮化生区内。癌旁组织与异型增生的化生改变相似。６５．１％的胆囊癌可见化生改变，分化好的胆囊癌化生出现率高于分化差的胆囊癌（Ｐ＜０．０１）。我们认为胆囊粘膜上皮化生与胆囊癌的组织发生有重要关系，且肠上皮化生尤为重要。
The relation between metaplasia and histogenesis of gallbladder carcinoma wasstudied by means of histochemical and immunonhistochemical in 134 cases of benignand malignant lesions of human gallbladder. Mataplasia was demonstrated in alldysplasias and most of the metaplasia were intestinal-type metaplasia. The metaplasia of hording areas of the carcinoma was same with dysplasia. Metaplasia represented in 65. 1% gallbladder carcinoma. The positive rate of metaplasia was lowerin poor-differential carcinomas (P<0. 01 ). The study suggested that intestinal-typemetaplasias of gallbladder epithelium was significantly related to development ofgallbladder carcinoma.
出处
《肿瘤防治研究》
CAS
CSCD
北大核心
1996年第1期16-17,共2页
Cancer Research on Prevention and Treatment
