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CYP19基因多态性与乳腺癌风险 被引量:2

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摘要 CYP19基因表达与雌激素的产生密切相关,突变可能会改变雌激素的暴露情况,影响乳腺癌的发病风险。CYP19基因是一个低外显率的基因,因此对于癌症发生的意义就更大。目前关于CYP19基因多态性与乳腺癌之间的关系仍存在争论,尚需深入研究以明确芳香化酶的基因多态性在乳腺癌发生中的作用,以及该基因多态性对芳香化酶功能的影响。
出处 《国际肿瘤学杂志》 CAS 2006年第2期128-131,共4页 Journal of International Oncology
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同被引文献21

  • 1成碟,徐为人,刘昌孝.细胞色素P450(CYP450)遗传多态性研究进展[J].中国药理学通报,2006,22(12):1409-1414. 被引量:44
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