摘要
目的探讨胆囊癌与胆囊结石的关系及胆囊结石伴胆囊癌的诊断和治疗特点。方法对1993年1月至2004年12月间收治的27例胆囊癌合并胆囊结石患者进行回顾性临床分析。结果27例胆囊癌合并胆囊结石患者,男10例,女17例,男女之比为1:1.7。平均年龄68.5岁,其中60岁以上22例。临床症状最常见为腹痛(85.2%)。既往有明确胆结石病史患者15例,入院后发现胆结石的有12例。行B超检查的23例,诊断胆囊癌的有12例(52.2%)。CT结合增强扫描检查12例.诊断胆囊癌的有8例(66.7%)。行肿瘤根治切除者8例,根治率29.6%。随访13例。随访期为3个月~7年,获随访者的平均存活时间为12个月。结论胆囊结石是胆囊癌的发病因素之一,胆囊癌早期诊断困难,晚期治疗效果差,伴胆囊结石的胆囊癌关键是要引起重视,不能满足胆囊结石的诊断而遗漏胆囊癌。对胆囊结石患者要密切随访,高危患者要尽早手术。
Objective To explore the relationship between gallbladder carcinoma and gallstones and the diagnosis and treatment of the gallbladder carcinoma associated with gallstones. Methods A retrospective clinical analysis was made in 27 cases of gallbladder carcinoma associated with gallstones, who were admitted to and treated in our hospital from Jan. 1993 to Dec. 2004. Results There were 10 males and 17 females with a male to female ratio of 1 : 1.7. Among the 27 cases, 22 cases ( 79.2% ) aged older than 60 years. The most frequent symptom was abdominal pain ( 85.2 % ). Fifteen cases had the history of gallstones. BUS images were obtained from 23 patients and the accuracy rate was 52.2%. CT images was obtained from 12 patients and the accuracy rate was 66.7%. The rate of radical resection was 29.6% (8 cases). The mean survival time was 12 months. Conclusion Gallstones is one of the most important pathologic conditions of gallbladder carcinoma. The early diagnosis of gallbladder carcinoma is difficult and the therapeutic efficacy is still not satisfactory. Attention should be paid to the diagnosis of gallstones and coexistent gallbladder carcinoma.
出处
《临床外科杂志》
2006年第2期100-102,共3页
Journal of Clinical Surgery
关键词
胆囊癌
胆囊结石
诊断
治疗
预防
gallbladder carcinoma
gallstones
diagnosis
treatment
prevention